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Her one line in the film was cut and her appearance exists only as a scene shown during the credit sequence.
A remake of the Japanese horror film Kairo, the film grossed US.9 million worldwide,; however it garnered negative response from critics.On July 29, 2007, during a train ride back to Los Angeles from the San Diego Comic-Con with Heroes actors Zachary Quinto and Masi Oka, and writers from the series, the writers had mentioned that if she "ever want[ed] to come on Heroes, give us [writers] a call," to which Bell said she would "love to." The casting of Bell, Heroes creator Tim Kring explained, "was not easy to pull off", but because of the large ensemble cast of the series and multiple story arcs, "we found a way to jump into a small window in [Bell's] schedule." Bell lent her voice to the CW series Gossip Girl: she voiced the title character in every episode of the series, appearing in person only for a surprise cameo in the final episode, portraying herself.Shortly after the cancellation of Veronica Mars in early 2007, Bell filmed on location in Hawaii for a starring role as the title character in the Judd Apatow comedy Forgetting Sarah Marshall. She began her acting career starring in stage productions and attended the Tisch School of Arts in New York.
In 2001, she made her Broadway debut as Becky Thatcher in The Adventures of Tom Sawyer and starred in the Broadway revival of The Crucible the following year.
In 1998, the year she graduated, Bell was named the yearbook's "Best Looking Girl" by senior class vote.